박하추출물의 구강미생물에 대한 항균효과
Effectiveness of mentha extracts against oral microorganisms: an in vitro study
최별보라, 윤세은, 박상례, 김규천,
소속 상세정보
최별보라 ( Choi Byul-Bo-Ra ) - Feagle Co. Ltd.
윤세은 ( Yun Se-Eun ) - Pusan National University School of Dentistry Department of Oral Anatomy
박상례 ( Park Sang-Rye ) - Kyungnam College of Information & Technology Department of Dental Hygiene
김규천 ( Kim Gyoo-Cheon ) - Pusan National University School of Dentistry Department of Oral Anatomy
Abstract
Objectives: Dental caries and periodontal disease are infectious and chronic diseases. The aim of the study was to investigate the antimicrobial effect of mentha extracts against Streptococcus mutans (S. mutans) and Porphyromonas gingivalis (P. gingivalis).
Methods: This activity of mentha extracts were confirmed by the disk diffusion test and minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and colony forming unit (CFU) assays.
Results: S. mutans and P. gingivalis showed the highest antimicrobial activity within the inhibition zones. The antimicrobial activity was interrupted as the MIC and MBC of the herbal extracts against the two bacteria were 1 mg/ml and 10 mg/ml, respectively. The antimicrobial effect was determined by the CFU assay.
Conclusions: Mentha herb extract demonstrated potential antimicrobial activity against S. mutans and P. gingivalis that cause dental caries and periodontal disease.
키워드
Antimicrobial effect; Mentha extracts; Porphyromonas gingivalis; Streptococcus mutans
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